反应详情

A solution of 2-(1-adamantyl)ethyl p-toluene-sulfonate (4.0 g) and sodium iodide (2.5 g) in 2-butanone (20 ml) is heated for 2 hours under reflux. The cooled solution is filtered and concentrated to a residue which is partitioned between dichloromethane and water. The organic layer is washed with aqueous sodium thiosulfate and water. The dried solution is evaporated to a crystalline mass which is recrystallized from ethanol to give 2-(1-adamantyl)ethyl iodide (2.0 g), m.p. 93°-94°. An analytical sample is obtained by recrystallization from the same solvent, m.p. 97°-98°.

1. temperatureunder reflux
2. filtrationThe cooled solution is filtered
3. concentrationconcentrated to a residue which
4. customis partitioned between dichloromethane and water
5. washThe organic layer is washed with aqueous sodium thiosulfate and water
6. customThe dried solution is evaporated to a crystalline mass which
7. customis recrystallized from ethanol