反应详情

20.4 parts by weight of benzenesulfochloride in 20 parts by volume of tetrahydrofurane were added dropwise at 10°-15°C over the course of 15 minutes to a stirred mixture of 10 parts by weight of 1,3-diaza-cyclohexane-2-one, 80 parts by volume of tetrahydrofurane and 80 parts by volume of chloroform, followed by 10.1 parts by weight of triethylamine at the same temperature. The mixture was stirred at 10°-15°C for 30 minutes and then overnight at 50°C. Subsequently the mixture was evaporated to dryness; the residue was stirred with 100 parts by volume of water, filtered, stirred with water once more, filtered and washed with ethanol.

1. customovernight
2. customat 50°C
3. customSubsequently the mixture was evaporated to dryness
4. stirringthe residue was stirred with 100 parts by volume of water
5. filtrationfiltered
6. stirringstirred with water once more
7. filtrationfiltered
8. washwashed with ethanol