Sodium Hydroxide → HCID 23714406, compound

HRID 128287Notes

Reaction equation

HRID 128287 reaction equation
Cl[C:2]1[C:3]2[CH:13]=[CH:12][C:11]([Cl:14])=[CH:10][C:4]=2[S:5][C:6]=1[C:7](Cl)=[O:8].[OH-:15].[Na+:16].[S:17]([O-:20])([OH:19])=[O:18].[Na+]>[Cu]Cl>[C:7]([C:6]1[S:5][C:4]2[CH:10]=[C:11]([Cl:14])[CH:12]=[CH:13][C:3]=2[C:2]=1[S:17]([O-:20])(=[O:19])=[O:18])([OH:15])=[O:8].[Na+:16]

Participants

5

Reactant 3

HCID 14798Sodium HydroxideHCID 27483283,6-Dichloro-1-benzothiophene-2-carbonyl chlorideHCID 23665763Sodium Bisulfite

Product 1

HCID 23714406HCID 23714406, compound

Reagents, catalysts & solvents 1

HCID 62652Cuprous chlorideCatalyst

Procedure

Prepared analogous to Example 1(a) from 3,6-dichlorobenzo[b]-thiophene-2-carboxylic acid chloride (m.p. 132°-133° C.) by hydrolysis with aqueous sodium hydroxide solution and subsequent reaction with sodium hydrogen sulfite in the presence of copper(I)-chloride as a catalyst.

Sources & evidence

ORD record
ord-e22eaed3d2bb48968bb6c051a2989f66
Source dataset
uspto-grants-1981_03
Patent number
US04259336

Reaction notes

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