反应详情

A stirred solution of (1-oxo-2-methyl-2-phenyl-6,7-dichloro-5-indanyloxy)acetic acid (5.48 g., 0.015 mole) and hydroxylamine hydrochloride (3.2 g., 0.045 mole) in pyridine (60 ml.) is heated at 95°C. on a steam bath for 36 hours then poured into aqueous hydrochloric acid affording (1-hydroximino-2-methyl-2-phenyl-6,7-dichloro-5-indanyloxy)acetic acid.