Hydrochloric Acid → HCID 86733821, compound

HRID 1283247Notes

Reaction equation

HRID 1283247 reaction equation
O=[C:2]1[C:10]2[C:5](=[CH:6][C:7]([O:13][CH2:14][C:15]([OH:17])=[O:16])=[C:8]([Cl:12])[C:9]=2[Cl:11])[CH2:4][C:3]1([CH3:24])[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1.Cl.[NH2:26][OH:27].Cl>N1C=CC=CC=1>[N:26](=[C:2]1[C:10]2[C:5](=[CH:6][C:7]([O:13][CH2:14][C:15]([OH:17])=[O:16])=[C:8]([Cl:12])[C:9]=2[Cl:11])[CH2:4][C:3]1([CH3:24])[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)[OH:27]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 42266IndacrinoneHCID 443297Hydroxyamine hydrochloride

Product 1

HCID 86733821HCID 86733821, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

A stirred solution of (1-oxo-2-methyl-2-phenyl-6,7-dichloro-5-indanyloxy)acetic acid (5.48 g., 0.015 mole) and hydroxylamine hydrochloride (3.2 g., 0.045 mole) in pyridine (60 ml.) is heated at 95°C. on a steam bath for 36 hours then poured into aqueous hydrochloric acid affording (1-hydroximino-2-methyl-2-phenyl-6,7-dichloro-5-indanyloxy)acetic acid.

Sources & evidence

ORD record
ord-056c13a1a46d46d68507bfb00ad3869f
Source dataset
uspto-grants-1976_08
Patent number
US03974212

Reaction notes

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