Hydrochloric Acid → HCID 21518485, compound

HRID 1283583Notes

Reaction equation

HRID 1283583 reaction equation
[O:1]1[CH2:6][CH2:5][N:4]([C:7]2[C:16]3[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=3)[CH:10]=[C:9](Cl)[N:8]=2)[CH2:3][CH2:2]1.[NH:18]1[CH2:23][CH2:22][NH:21][CH2:20][CH2:19]1.Cl>O>[O:1]1[CH2:6][CH2:5][N:4]([C:7]2[C:16]3[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=3)[CH:10]=[C:9]([N:18]3[CH2:23][CH2:22][NH:21][CH2:20][CH2:19]3)[N:8]=2)[CH2:3][CH2:2]1

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 4837PiperazineHCID 21518465HCID 21518465, compound

Product 1

HCID 21518485HCID 21518485, compoundYield 26%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

1-Morpholino-3-piperazino-isoquinoline was prepared analogous to Example 3 from 1 -morpholino-3-chloro-isoquinoline and piperazine. M.p. of its hydrochloride: 245°-247°C (from water); yield: 26% of theory.

Sources & evidence

ORD record
ord-cd2acb5860af4b84a3b1a50cf145d2e4
Source dataset
uspto-grants-1976_08
Patent number
US03975524

Reaction notes

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