Formaldehyde → HCID 21454000, compound

HRID 1283827Notes

Reaction equation

HRID 1283827 reaction equation
[CH2:1]=O.[NH2:3][C:4]([CH3:8])([CH3:7])[CH2:5][OH:6].C([O-])(=O)C.[Zn+2:13].[C:14]([O-])(=O)C.[C:18](=[S:20])=[S:19]>C(O)(C)C>[CH3:7][C:4]1([CH3:8])[CH2:5][O:6][CH2:1][N:3]1[C:18]([S-:20])=[S:19].[CH3:7][C:4]1([CH3:8])[CH2:5][O:6][CH2:14][N:3]1[C:18]([S-:20])=[S:19].[Zn+2:13]

Participants

6

Reactant 4

HCID 712Formaldehyde2×HCID 6348Carbon DisulfideHCID 11192Zinc AcetateHCID 118072-Amino-2-methyl-1-propanol

Product 1

HCID 21454000HCID 21454000, compound

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Conditions

Temperature
12 °C

Procedure

Thirty grams (1.0 mole) paraformaldehyde was added to a solution of 89.2 g. (1.0 mole) 2-amino-2-methyl-1-propanol in 600 ml. isopropanol, temperature at 45°-64°C. After all the paraformaldehyde had dissolved, the mixture was cooled to 12°C.; 92 g. (0.50 mole) anhydrous zinc acetate and 76 g. (1.0 mole) carbon disulfide was added. The reaction mixture was stirred six hours at 45°-50°C. Filtration at 5°C. gave 152.6 g. of the desired product melting with decomposition at 209°-211°C. A benzene-crystallized sample had the following analysis:

Workup

  1. customat 45°-64°C
  2. filtrationFiltration at 5°C.
  3. customgave 152.6 g

Sources & evidence

ORD record
ord-47cc17d837984fec8f0f5a099ab43f5c
Source dataset
uspto-grants-1976_08
Patent number
US03976648

Reaction notes

Loading…