Water → HCID 21516782, compound

HRID 1283873Notes

Reaction equation

HRID 1283873 reaction equation
[CH2:1]([CH:3]1[C:11](=[O:12])[C:10]2[C:5](=[CH:6][C:7]([O:15][CH3:16])=[C:8]([Cl:14])[C:9]=2[Cl:13])[C:4]1=[O:17])[CH3:2].[C:18](=O)([O-])[O-].[K+].[K+].CI.O>CN(C)C=O>[CH2:1]([C:3]1([CH3:18])[C:11](=[O:12])[C:10]2[C:5](=[CH:6][C:7]([O:15][CH3:16])=[C:8]([Cl:14])[C:9]=2[Cl:13])[C:4]1=[O:17])[CH3:2]

Participants

6

Reactant 4

HCID 962WaterHCID 6328Methyl iodideHCID 11430Potassium CarbonateHCID 21516783HCID 21516783, compound

Product 1

HCID 21516782HCID 21516782, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

A stirred solution of 2-ethyl-4,5-dichloro-6-methoxyindan-1,3-dione (1.3 g.) in dimethylformamide (15 ml.) is treated with potassium carbonate (1.26 g.) and methyl iodide. After 15 minutes, the reaction is poured into water (75 ml.) affording 1.3 g. of 2-ethyl-2-methyl-4,5-dichloro-6-methoxyindan-1,3-dione which melts at 157°C. after recrystallization from ethanol.

Workup

  1. customaffording 1.3 g
  2. customof 2-ethyl-2-methyl-4,5-dichloro-6-methoxyindan-1,3-dione which melts at 157°C. after recrystallization from ethanol

Sources & evidence

ORD record
ord-4124aede3d23497882e155e3923f8619
Source dataset
uspto-grants-1976_08
Patent number
US03976681

Reaction notes

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