Hydrazine hydrate (1:1) → 5-Hydrazino-1,3-dihydropyrrolo[4,3,2-de]isoquinoline

HRID 1284033Notes

Reaction equation

HRID 1284033 reaction equation
C(O[C:4]1[C:13]2[CH:12]=[CH:11][CH:10]=[C:9]3[NH:14][CH:15]=[C:7]([C:8]=23)[CH2:6][N:5]=1)C.O.[NH2:17][NH2:18]>CO>[NH:17]([C:4]1[C:13]2[CH:12]=[CH:11][CH:10]=[C:9]3[NH:14][CH:15]=[C:7]([C:8]=23)[CH2:6][N:5]=1)[NH2:18]

Participants

4

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 215155225-Ethoxy-1,3-dihydropyrrolo[4,3,2-de]isoquinoline

Product 1

HCID 30410875-Hydrazino-1,3-dihydropyrrolo[4,3,2-de]isoquinoline

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Similarly, treatment of equimolar amounts of 5-ethoxy-1,3-dihydropyrrolo[4,3,2-de]isoquinoline hydrofluoroborate, described in Example 5, and hydrazine hydrate in methanol gives 5-hydrazino-1,3-dihydropyrrolo[4,3,2-de]isoquinoline hydrofluoroborate, mp 263° - 265°C.

Sources & evidence

ORD record
ord-36039045e4a14bdcbc0f6ec466bb196b
Source dataset
uspto-grants-1976_08
Patent number
US03978066

Reaction notes

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