Hydrochloric Acid → HCID 86733883, compound

HRID 1284153Notes

Reaction equation

HRID 1284153 reaction equation
[Cl:1][CH:2]1[O:14][C:3]1([CH3:13])[CH:4]([C:9]([O:11]C)=[CH2:10])[CH2:5]/[CH:6]=[CH:7]\[CH3:8].Cl>O1CCCC1>[Cl:1][CH:2]1[O:14][C:3]1([CH3:13])[CH:4]([C:9](=[O:11])[CH3:10])[CH2:5]/[CH:6]=[CH:7]\[CH3:8]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 86733882HCID 86733882, compound

Product 1

HCID 86733883HCID 86733883, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

A solution of 6.75 g. (31.5 mmol.) of crude (Z)-1-chloro-1,2-epoxy-2-methyl-3-(1-methoxy-ethenyl)-5-heptene in 350 ml. of 2:1 tetrahydrofuran: 10% by weight aqueous hydrochloric acid was stirred at room temperature for 30 minutes, concentrated, extracted with diethyl ether, the ethereal extracts washed with water and saturated aqueous sodium chloride, dried (Na2SO4) and concentrated to afford (Z)-1-chloro-1,2-epoxy-2-methyl-3-acetyl-5-heptene as a yellow oil.

Workup

  1. concentrationconcentrated
  2. extractionextracted with diethyl ether
  3. washthe ethereal extracts washed with water and saturated aqueous sodium chloride
  4. dry with materialdried (Na2SO4)
  5. concentrationconcentrated

Sources & evidence

ORD record
ord-2406accf159941c2b33661fb1d680162
Source dataset
uspto-grants-1976_08
Patent number
US03978093

Reaction notes

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