反应详情

The compound (VI) is prepared by reacting the compound (VIII) with a 1 to 2 equivalent amount of sodium nitrite in a solvent (e.g. sulfuric acid, hydrochloric acid, acetic acid, water) at a temperature of 0° to 20° C. for a period of 5 minutes to 5 hours to obtain its diazonium salt, followed by hydrolysis of the diazonium salt in dilute sulfuric acid at a temperature of 20° to 100° C. In the hydrolysis, a copper compound such as cuprous oxide or cupric nitrate may be used in place of dilute sulfuric acid.

1. customat a temperature of 0° to 20° C.
2. customof 5 minutes to 5 hours