Methyl iodide → Ethyl 2-[4-(2-thienyl-methoxyiminomethyl)-phenoxy]-2-methyl-propionate

HRID 128471Notes

Reaction equation

HRID 128471 reaction equation
[CH3:1]I.[S:3]1[CH:7]=[CH:6][CH:5]=[C:4]1[C:8](=[N:24][OH:25])[C:9]1[CH:23]=[CH:22][C:12]([O:13][C:14]([CH3:21])([CH3:20])[C:15]([O:17][CH2:18][CH3:19])=[O:16])=[CH:11][CH:10]=1>CN(C)C=O.C(=O)([O-])[O-].[K+].[K+]>[S:3]1[CH:7]=[CH:6][CH:5]=[C:4]1[C:8](=[N:24][O:25][CH3:1])[C:9]1[CH:23]=[CH:22][C:12]([O:13][C:14]([CH3:21])([CH3:20])[C:15]([O:17][CH2:18][CH3:19])=[O:16])=[CH:11][CH:10]=1

Participants

5

Reactant 2

HCID 6328Methyl iodideHCID 86737662Ethyl 2-[4-(2-thienyl-hydroxyiminomethyl)-phenoxy]-2-methyl-propionate

Product 1

HCID 53877118Ethyl 2-[4-(2-thienyl-methoxyiminomethyl)-phenoxy]-2-methyl-propionate

Reagents, catalysts & solvents 2

HCID 6228DimethylformamideSolventHCID 11430Potassium CarbonateSolvent

Procedure

This oily compound, which consists of a mixture of both isomers Z/E, is obtained by reacting methyl iodide with ethyl 2-[4-(2-thienyl-hydroxyiminomethyl)-phenoxy]-2-methyl-propionate dissolved in dimethyl formamide and in the presence of potassium carbonate.

Workup

  1. additionThis oily compound, which consists of a mixture of both isomers Z/E
  2. customis obtained

Sources & evidence

ORD record
ord-04c21f4f877441268b7c62cdd51025d9
Source dataset
uspto-grants-1981_03
Patent number
US04259509

Reaction notes

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