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HRID1285167

反应详情

EQUATION

反应方程式

HRID 1285167 的结构方程式

REACTANTS

反应物

3
结构：Cn1c(=O)c2c(ncn2CC(N)=NO)n(C)c1=O
HCID3057490

未命名化合物

结构：C[O-].[Na+]
HCID10942334

Methanol, sodium salt

CH3NaO

结构：CCOC(=O)C(C)N(CC)CC
HCID13010788

未命名化合物

PRODUCTS

生成物

1
结构：CCN(CC)CCc1nc(Cn2cnc3c2c(=O)n(C)c(=O)n3C)no1
HCID11971033

1H-Purine-2,6-dione, 3,7-dihydro-7-((5-(2-(diethylamino)ethyl)-1,2,4-oxadiazol-3-yl)methyl)-1,3-dimethyl-

C16H23N7O3

收率 87%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：Cc1ccccc1
溶剂HCID1140

Toluene

C7H8

PROCEDURE

实验过程

5.04 g. of 2-(theophyllin-7-yl)-acetamidoxime, 2.16 g. of sodium methylate, 6.4 g. of diethylamino propionic acid ethyl ester and 100 cm3 of toluene are reacted according to Example a. 6.3 g. (87% yield) of 7-[{5-(2-diethylamino-ethan-1-yl)-1,2,4-oxadiazol-3-yl}-methyl]-theophylline are obtained. M.p.: 69°-70° C. (cyclohexane).