huagongshe.com
HRID1285360

反应详情

EQUATION

反应方程式

HRID 1285360 的结构方程式

REACTANTS

反应物

1
结构：CC(C)(C)OC(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)OCc1ccccc1
HCID13091041

未命名化合物

PRODUCTS

生成物

2
结构：O=C(OCc1ccccc1)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1
HCID11130444

未命名化合物

结构：CC(C)O.CCOC(C)=O
HCID22055037

未命名化合物

收率 342.9%

AUXILIARIES

试剂、催化剂与溶剂

2
结构：CC(=O)O
溶剂HCID176

Acetic Acid

C2H4O2

结构：Cl
溶剂HCID313

Hydrochloric Acid

ClH

PROCEDURE

实验过程

34.21 g (85 mmol) of BOC-Pro-Pro-OBzl (VII) were dissolved in 342 ml of a saturated solution of hydrogen chloride in acetic acid at room temperature. After 30 minutes BOC-removal was complete and the solvent was removed in vacuo. From iPrOH/AcOEt 21.60 g (75% yield) of compund VIII were obtained: RfD 0.32; E1.2 1.12.

WORKUP

后处理

  1. customAfter 30 minutes BOC-removal
  2. customthe solvent was removed in vacuo