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HRID1285361

反应详情

EQUATION

反应方程式

HRID 1285361 的结构方程式

REACTANTS

反应物

3
结构：Cl
HCID313

Hydrochloric Acid

ClH

结构：CC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)O
HCID83693

L-Valine, N-[(1,1-dimethylethoxy)carbonyl]-

C10H19NO4

结构：O=C(OCc1ccccc1)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1
HCID11130444

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)OCc1ccccc1
HCID13988140

未命名化合物

收率 70%

PROCEDURE

实验过程

Starting from 13.79 g (63.45 mmol) of BOC-Val-OH and 21.5 g (63.45 mmol) of HCl.H-Pro-Pro-OBzl (VIII) and operating as described in Step 7, 22.28 g (70% yield) of compound IX were obtained as an oil after purification by column chromatography on silica gel (Merck) 0.040-0.063 mm eluting with ethyl acetate: methanol=98:2.