Aniline → Aniline

HRID 1285754Notes

Reaction equation

HRID 1285754 reaction equation
Brc1cccnc1.Nc1ccccc1>CC(C)(C)N=P(N1CCCC1)(N1CCCC1)N1CCCC1.CC(C)(C)[P](C(C)(C)C)(C(C)(C)C)->[Pd]1([Cl])<-[NH2]c2ccccc2-c2cccc[c]21.CS(C)=O>c1ccc(Nc2cccnc2)cc1

Participants

9

Reactant 2

HCID 6115AnilineHCID 122863-Bromopyridine

Product 4

HCID 6115AnilineHCID 7095BiphenylHCID 122863-BromopyridineHCID 4712169Phenyl-pyridin-3-yl-amine

Reagents, catalysts & solvents 3

HCID 3856267tert-Butylimino-tri(pyrrolidino)phosphoraneReagentHCID 178454887HCID 178454887, compoundReagentHCID 679Dimethyl SulfoxideSolvent4×

Procedure

The Mosquito was used to combine the source plate solutions by multi-aspiration of 250 nL of each of the four reaction components and then to dose the resulting reaction mixture (1 uL) into a 1536-well plate

Workup

  1. additionNo procedure recorded
  2. aliquotNo procedure recorded
  3. additionNo procedure recorded

Sources & evidence

ORD record
ord-87a68220190a4892b0b5c1bec0e8d009
Source dataset
HTE Pd-catalyzed cross-coupling screen
Original link
View source

Reaction notes

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