Benzamide → Benzamide

HRID 1285830Notes

Reaction equation

HRID 1285830 reaction equation
Brc1cccnc1.NC(=O)c1ccccc1>CN(C)C(=NC(C)(C)C)N(C)C.CS(=O)(=O)[O][Pd]1(<-[NH2]c2ccccc2-c2cccc[c]21)<-[P](c1ccccc1)(c1ccccc1)c1ccc2ccccc2c1-c1c(P(c2ccccc2)c2ccccc2)ccc2ccccc12.CS(C)=O>O=C(Nc1cccnc1)c1ccccc1

Participants

9

Reactant 2

HCID 2331BenzamideHCID 122863-Bromopyridine

Product 4

HCID 2331BenzamideHCID 7095BiphenylHCID 122863-BromopyridineHCID 293813N-pyridin-3-ylbenzamide

Reagents, catalysts & solvents 3

HCID 35715812-tert-Butyl-1,1,3,3-tetramethylguanidineReagentHCID 178505363HCID 178505363, compoundReagentHCID 679Dimethyl SulfoxideSolvent4×

Procedure

The Mosquito was used to combine the source plate solutions by multi-aspiration of 250 nL of each of the four reaction components and then to dose the resulting reaction mixture (1 uL) into a 1536-well plate

Workup

  1. additionNo procedure recorded
  2. aliquotNo procedure recorded
  3. additionNo procedure recorded

Sources & evidence

ORD record
ord-e7312f77d2d940a1a732552831d23a4a
Source dataset
HTE Pd-catalyzed cross-coupling screen
Original link
View source

Reaction notes

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