Benzamide → Benzamide

HRID 1285874Notes

Reaction equation

HRID 1285874 reaction equation
Brc1cccnc1.NC(=O)c1ccccc1>CC(C)(C)N=P(N1CCCC1)(N1CCCC1)N1CCCC1.CC(C)Oc1cccc(OC(C)C)c1-c1ccccc1[P](C1CCCCC1)(C1CCCCC1)->[Pd]1([Cl])<-[NH2]c2ccccc2-c2cccc[c]21.CS(C)=O>O=C(Nc1cccnc1)c1ccccc1

Participants

9

Reactant 2

HCID 2331BenzamideHCID 122863-Bromopyridine

Product 4

HCID 2331BenzamideHCID 7095BiphenylHCID 122863-BromopyridineHCID 293813N-pyridin-3-ylbenzamide

Reagents, catalysts & solvents 3

HCID 3856267tert-Butylimino-tri(pyrrolidino)phosphoraneReagentHCID 178458463HCID 178458463, compoundReagentHCID 679Dimethyl SulfoxideSolvent4×

Procedure

The Mosquito was used to combine the source plate solutions by multi-aspiration of 250 nL of each of the four reaction components and then to dose the resulting reaction mixture (1 uL) into a 1536-well plate

Workup

  1. additionNo procedure recorded
  2. aliquotNo procedure recorded
  3. additionNo procedure recorded

Sources & evidence

ORD record
ord-104ec548448a4c3da4bb1c18bfcdd67f
Source dataset
HTE Pd-catalyzed cross-coupling screen
Original link
View source

Reaction notes

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