Phenol → Phenol

HRID 1286543Notes

Reaction equation

HRID 1286543 reaction equation
Brc1cccnc1.Oc1ccccc1>CC(C)Oc1cccc(OC(C)C)c1-c1ccccc1[P](C1CCCCC1)(C1CCCCC1)->[Pd]1([Cl])<-[NH2]c2ccccc2-c2cccc[c]21.CN1CCCN2CCCN=C12.CS(C)=O>c1ccc(Oc2cccnc2)cc1

Participants

9

Reactant 2

HCID 996PhenolHCID 122863-Bromopyridine

Product 4

HCID 996PhenolHCID 7095BiphenylHCID 122863-BromopyridineHCID 2005103-Phenoxypyridine

Reagents, catalysts & solvents 3

HCID 1235837-Methyl-1,5,7-triazabicyclo[4.4.0]dec-5-eneReagentHCID 178458463HCID 178458463, compoundReagentHCID 679Dimethyl SulfoxideSolvent4×

Procedure

The Mosquito was used to combine the source plate solutions by multi-aspiration of 250 nL of each of the four reaction components and then to dose the resulting reaction mixture (1 uL) into a 1536-well plate

Workup

  1. additionNo procedure recorded
  2. aliquotNo procedure recorded
  3. additionNo procedure recorded

Sources & evidence

ORD record
ord-2d475476ba47463d98243ae68cf09428
Source dataset
HTE Pd-catalyzed cross-coupling screen
Original link
View source

Reaction notes

Loading…