Acetic Anhydride → 3-Cyclohexen-1-ol, 3,5,5-trimethyl-, acetate

HRID 1287173노트

반응식

HRID 1287173 반응식
[BH4-].[Na+].[CH3:3][C:4]1[CH2:10][C:8](=[O:9])[CH2:7][C:6]([CH3:12])([CH3:11])[CH:5]=1.CC1[CH2:15][CH:16]([OH:22])CC(C)(C)C=1.C(OC(=O)C)(=O)C.C([O-])(=O)C.[Na+]>CO>[C:16]([O:9][CH:8]1[CH2:7][C:6]([CH3:12])([CH3:11])[CH:5]=[C:4]([CH3:3])[CH2:10]1)(=[O:22])[CH3:15]

참가 물질

7

반응물 5

HCID 7918Acetic AnhydrideHCID 10108Beta-IsophoroneHCID 517045Sodium AcetateHCID 4311764Sodium borohydrideHCID 112750493,5,5-Trimethylcyclohex-3-en-1-ol

생성물 1

HCID 907913-Cyclohexen-1-ol, 3,5,5-trimethyl-, acetate

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

Prepared by reduction by means of sodium borohydride in methanol of β-isophorone [obtained according to J. Am. Chem. Soc., 63, 2308 (1941)] and subsequent acetylation of the obtained 3,5,5-trimethyl-cyclohex-3-en-1-ol by means of acetic anhydride in the presence of sodium acetate at 50°C during 20 hours. NMR (CCl4): 1.0 (6H,s); 1.62 (3H,s); 1.92 (3H,s); 5.10 (1H,s); 4.6-5.2 (1H,m) δ ppm

출처 및 근거

ORD 기록
ord-e220c05ecf724006b4901de3f744f487
출처 데이터셋
uspto-grants-1976_10
특허 번호
US03983885

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