Chlorophenyl isocyanate → HCID 152745232, compound

HRID 1287377Notes

Reaction equation

HRID 1287377 reaction equation
[Na].Cl.[C:3]([NH2:9])(=[NH:8])[CH2:4][CH2:5][CH2:6][CH3:7].[Cl:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=1[N:17]=[C:18]=[O:19]>CC(C)=O>[Cl:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=1[NH:17][C:18]([NH:8][C:3](=[NH:9])[CH2:4][CH2:5][CH2:6][CH3:7])=[O:19]

Participants

5

Reactant 3

HCID 76833Chlorophenyl isocyanateHCID 5360545SodiumHCID 11615174Pentanimidamide Hydrochloride

Product 1

HCID 152745232HCID 152745232, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent2×

Procedure

Following a procedure similar to that described in Example 1 but using 2.3 g. sodium in 250 ml. dry acetone, 13.6 g. valeramidine hydrochloride, and 15.3 g. 2-chlorophenyl isocyanate in 100 ml. dry acetone, there was obtained after recrystallization from isopropyl alcohol-ether 15.4 g. of the hydrochloride of 1-(2-chloropheyl)-3-(pentanimidoyl)yrea; m.p. 132°-134°C.

Workup

  1. customafter recrystallization from isopropyl alcohol-ether 15.4 g

Sources & evidence

ORD record
ord-8ac5c77aaca7416d863667685d42f5ae
Source dataset
uspto-grants-1976_10
Patent number
US03984467

Reaction notes

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