3,4-Dichlorophenyl isocyanate → HCID 152745873, compound

HRID 1287378Notes

Reaction equation

HRID 1287378 reaction equation
[Na].Cl.[C:3]([NH2:9])(=[NH:8])[CH2:4][CH2:5][CH2:6][CH3:7].[Cl:10][C:11]1[CH:12]=[C:13]([N:18]=[C:19]=[O:20])[CH:14]=[CH:15][C:16]=1[Cl:17]>CC(C)=O>[Cl:10][C:11]1[CH:12]=[C:13]([NH:18][C:19]([NH:8][C:3](=[NH:9])[CH2:4][CH2:5][CH2:6][CH3:7])=[O:20])[CH:14]=[CH:15][C:16]=1[Cl:17]

Participants

5

Reactant 3

HCID 76073,4-Dichlorophenyl isocyanateHCID 5360545SodiumHCID 11615174Pentanimidamide Hydrochloride

Product 1

HCID 152745873HCID 152745873, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent2×

Procedure

Following a procedure similar to that described in Example 1 but using 3.39 g. sodium in 200 ml. dry acetone, 20 g. valeramidine hydrochloride, and 27.6 g. 3,4-dichlorophenyl isocyanate in 100 ml. dry acetone, there was obtained after recrystallization from acetone 10.5 g. of the hydrochloride of 1-(3,4-dichlorophenyl)-3-(pentanimidoyl)urea; m.p. 177°-179°C.

Workup

  1. customafter recrystallization from acetone 10.5 g

Sources & evidence

ORD record
ord-a597ad27cdbd44cabb8c86e73ea5e928
Source dataset
uspto-grants-1976_10
Patent number
US03984467

Reaction notes

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