Benzene, 1-isocyanato-4-nitro- → HCID 152747114, compound

HRID 1287380Notes

Reaction equation

HRID 1287380 reaction equation
[Na].Cl.[C:3]([NH2:9])(=[NH:8])[CH2:4][CH2:5][CH2:6][CH3:7].[N+:10]([C:13]1[CH:18]=[CH:17][C:16]([N:19]=[C:20]=[O:21])=[CH:15][CH:14]=1)([O-:12])=[O:11]>CC(C)=O>[N+:10]([C:13]1[CH:14]=[CH:15][C:16]([NH:19][C:20]([NH:8][C:3](=[NH:9])[CH2:4][CH2:5][CH2:6][CH3:7])=[O:21])=[CH:17][CH:18]=1)([O-:12])=[O:11]

Participants

5

Reactant 3

HCID 66012Benzene, 1-isocyanato-4-nitro-HCID 5360545SodiumHCID 11615174Pentanimidamide Hydrochloride

Product 1

HCID 152747114HCID 152747114, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent2×

Procedure

Following a procedure similar to that described in Example 1 but using 3.39 g. sodium in 200 ml. dry acetone, 20 g. valeramidine hydrochloride, and 21.9 g. 4-nitrophenyl isocyanate in 100 ml. dry acetone, there was obtained after recrystallization from methyl alcohol 10.8 g. of the hydrochloride of 1-(4-nitrophenyl)-3(-pentanimidoyl)urea; m.p. 187°-191°C.

Workup

  1. customafter recrystallization from methyl alcohol 10.8 g

Sources & evidence

ORD record
ord-85618ed00bf94c3caefa7e7aa06939d6
Source dataset
uspto-grants-1976_10
Patent number
US03984467

Reaction notes

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