Benzene, 1-chloro-3-isocyanato- → HCID 152746173, compound

HRID 1287382Notes

Reaction equation

HRID 1287382 reaction equation
[Na].Cl.[C:3]([NH2:9])(=[NH:8])[CH2:4][CH2:5][CH2:6][CH3:7].[Cl:10][C:11]1[CH:12]=[C:13]([N:17]=[C:18]=[O:19])[CH:14]=[CH:15][CH:16]=1>CC(C)=O>[Cl:10][C:11]1[CH:12]=[C:13]([NH:17][C:18]([NH:8][C:3](=[NH:9])[CH2:4][CH2:5][CH2:6][CH3:7])=[O:19])[CH:14]=[CH:15][CH:16]=1

Participants

5

Reactant 3

HCID 17968Benzene, 1-chloro-3-isocyanato-HCID 5360545SodiumHCID 11615174Pentanimidamide Hydrochloride

Product 1

HCID 152746173HCID 152746173, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent2×

Procedure

Following a procedure similar to that described in Example 1 but using 6.9 g. sodium in 300 ml. dry acetone, 41.1 g. valeramidine hydrochloride, and 46.2 g. 3-chlorophenyl isocyanate in 200 ml. dry acetone, there was obtained after recrystallization from acetone 27.1 g. of tjhe hydrochloride of 1-(3-chlorophenyl)-3-(pentanimidoyl)urea; m.p. 135°-137°C.

Workup

  1. customafter recrystallization from acetone 27.1 g

Sources & evidence

ORD record
ord-0c9b241bc4b94459adef2d4707295fe3
Source dataset
uspto-grants-1976_10
Patent number
US03984467

Reaction notes

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