Phenyl isocyanate → HCID 152750107, compound

HRID 1287389Notes

Reaction equation

HRID 1287389 reaction equation
[Na].Cl.[C:3]([NH2:9])(=[NH:8])[CH2:4][CH2:5][CH2:6][CH3:7].[C:10]1([N:16]=[C:17]=[O:18])[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1>CC(C)=O>[C:10]1([NH:16][C:17]([NH:8][C:3](=[NH:9])[CH2:4][CH2:5][CH2:6][CH3:7])=[O:18])[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1

Participants

5

Reactant 3

HCID 7672Phenyl isocyanateHCID 5360545SodiumHCID 11615174Pentanimidamide Hydrochloride

Product 1

HCID 152750107HCID 152750107, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent2×

Procedure

Following a procedure similar to that described in Example 23 but using 6.9 g. sodium in 300 ml. dry acetone, 41.1 g. valeramidine hydrochloride, and 35.7 g. phenyl isocyanate in 200 ml. dry acetone, there was obtained after recrystallization from ethyl alcohol 40.3 g. 1-phenyl-3-(pentanimidoyl)urea hydrochloride; m.p. 155.5°-156°C.

Workup

  1. customafter recrystallization from ethyl alcohol 40.3 g

Sources & evidence

ORD record
ord-8cc68c00677f44e08aead840e0a18f54
Source dataset
uspto-grants-1976_10
Patent number
US03984467

Reaction notes

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