Phenyl isocyanate → HCID 152750100, compound

HRID 1287391Notes

Reaction equation

HRID 1287391 reaction equation
[Na].Cl.[C:3]([NH2:6])(=[NH:5])[CH3:4].[C:7]1([N:13]=[C:14]=[O:15])[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1>CC(C)=O>[C:7]1([NH:13][C:14]([NH:5][C:3](=[NH:6])[CH3:4])=[O:15])[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1

Participants

5

Reactant 3

HCID 7672Phenyl isocyanateHCID 67170Acetamidine monohydrochlorideHCID 5360545Sodium

Product 1

HCID 152750100HCID 152750100, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent2×

Procedure

Following a procedure similar to that described in Example 23 but using 4.6 g. sodium in 500 ml. dry acetone, 18.8 g. acetamidine hydrochloride and 23.8 g. phenyl isocyanate in 100 ml. dry acetone, there was obtained after recrystallization from isopropyl alcohol 27.1 g. 1-phenyl-3-(acetimidoyl)urea hydrochloride; m.p. 204°-206°C.

Workup

  1. customafter recrystallization from isopropyl alcohol 27.1 g

Sources & evidence

ORD record
ord-a0d8a2bb3f4d4497a764216f47ebddf7
Source dataset
uspto-grants-1976_10
Patent number
US03984467

Reaction notes

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