Butyl isocyanate → HCID 152748181, compound

HRID 1287398Notes

Reaction equation

HRID 1287398 reaction equation
[Na].Cl.[C:3]([NH2:11])(=[NH:10])[C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1.[CH2:12]([N:16]=[C:17]=[O:18])[CH2:13][CH2:14][CH3:15]>CC(C)=O>[CH2:12]([NH:16][C:17]([NH:10][C:3](=[NH:11])[C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1)=[O:18])[CH2:13][CH2:14][CH3:15]

Participants

5

Reactant 3

HCID 8110Butyl isocyanateHCID 80289Benzamidine, hydrochlorideHCID 5360545Sodium2×

Product 1

HCID 152748181HCID 152748181, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

Following a procedure similar to that described in Example 23 but using 7.7 g. sodium in 1100 ml. dry sodium, 52.4 g. benzamidine hydrochloride, and 33.1 g. butylisocyanate in 400 ml. dry acetone there was obtained, after recrystallization from ethyl acetate, 62.2 g. 1-butyl-3-(benzimidoyl)urea hydrochloride; m.p. 139°-141°C.

Workup

  1. customafter recrystallization from ethyl acetate, 62.2 g

Sources & evidence

ORD record
ord-4cf6b54dfb5d4e788e781efd6f02028a
Source dataset
uspto-grants-1976_10
Patent number
US03984467

Reaction notes

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