Sulfuric Acid → HCID 21505996, compound

HRID 1287787Notes

Reaction equation

HRID 1287787 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]([CH:8]=[C:9]([S:18](=[O:21])(=[O:20])[NH2:19])[C:10]=1[O:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[C:5]([OH:7])=[O:6].S(=O)(=O)(O)O>C(O)CCCC>[CH2:9]([NH:1][C:2]1[CH:3]=[C:4]([CH:8]=[C:9]([S:18](=[O:21])(=[O:20])[NH2:19])[C:10]=1[O:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[C:5]([O:7][CH2:14][CH2:13][CH2:12][CH2:17][CH3:16])=[O:6])[CH2:10][CH2:2][CH2:3][CH3:4]

Participants

4

Reactant 2

HCID 1118Sulfuric AcidHCID 1199273-Amino-4-phenoxy-5-sulfamoylbenzoic acid

Product 1

HCID 21505996HCID 21505996, compound

Reagents, catalysts & solvents 1

HCID 62761-PentanolSolvent

Procedure

A mixture of 3-amino-4-phenoxy-5-sulphamyl-benzoic acid (6 g), n-pentanol (60 ml), and conc. sulphuric acid (0.5 ml) was refluxed for 24 hours. After cooling, the precipitated n-pentyl 3-pentylamino-4-phenoxy-5-sulphamyl-benzoate was isolated by filtration and recrystallized from n-pentanol. After drying in vacuo, the compound was obtained with a melting point of 138°-139° C.

Workup

  1. temperaturewas refluxed for 24 hours
  2. temperatureAfter cooling

Sources & evidence

ORD record
ord-a7494207e4014e0195975bdb5620cb0e
Source dataset
uspto-grants-1976_10
Patent number
US03985777

Reaction notes

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