Methyl chloroacetate → HCID 21506545, compound

HRID 1287838Notes

Reaction equation

HRID 1287838 reaction equation
[Cl:1][C:2]1[CH:15]=[CH:14][C:5]([O:6][C:7]2[CH:12]=[CH:11][C:10]([OH:13])=[CH:9][CH:8]=2)=[CH:4][CH:3]=1.C(=O)([O-])[O-].[K+].[K+].Cl[CH2:23][C:24]([O:26][CH3:27])=[O:25]>C(C(C)=O)C>[Cl:1][C:2]1[CH:15]=[CH:14][C:5]([O:6][C:7]2[CH:12]=[CH:11][C:10]([O:13][CH2:23][C:24]([O:26][CH3:27])=[O:25])=[CH:9][CH:8]=2)=[CH:4][CH:3]=1

Participants

5

Reactant 3

HCID 7295Methyl chloroacetateHCID 11430Potassium CarbonateHCID 123461204-(4-Chlorophenoxy)phenol

Product 1

HCID 21506545HCID 21506545, compoundYield 92.2%

Reagents, catalysts & solvents 1

HCID 6569Methyl Ethyl KetoneSolvent

Procedure

6.6 g (30 millimols) of 4-(4'-chlorophenoxy)phenol, 4.14 g (30 millimols) of potassium carbonate, 60 ml. of methyl ethyl ketone and 5.0 g (45 millimols) of methyl chloroacetate were treated in the same way as in Referential Example 2 to afford 8.1 g of oily methyl 4-(4'-chlorophenoxy)phenoxyacetate in a yield of 92%.

Sources & evidence

ORD record
ord-b68933ac111945b089d698ec93d83a2d
Source dataset
uspto-grants-1976_10
Patent number
US03985875

Reaction notes

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