Ethanol → HCID 85438861, compound

HRID 1288020Notes

Reaction equation

HRID 1288020 reaction equation
Cl.[NH2:2][OH:3].CO.[CH3:6][N:7]1[C:11]([CH:12]=O)=[CH:10][N:9]=[C:8]1[N+:14]([O-:16])=[O:15].C(O)C>C(N(CC)CC)C>[CH3:6][N:7]1[C:11]([CH:12]=[N:2][OH:3])=[CH:10][N:9]=[C:8]1[N+:14]([O-:16])=[O:15]

Participants

6

Reactant 4

HCID 702EthanolHCID 887MethanolHCID 1003901-Methyl-2-nitro-1H-imidazole-5-carboxaldehydeHCID 443297Hydroxyamine hydrochloride

Product 1

HCID 85438861HCID 85438861, compound

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

To a solution of 0.400 g. of hydroxylamine hydrochloride in 15 ml. of methanol, 0.400 g. of 1-methyl-2-nitro-5-imidazolcarboxaldehyde in 20 ml. of ethanol and 0.810 ml. of triethylamine are added at room temperature. After standing overnight, the solution is concentrated to a small volume and the solid which precipitates is collected on the filter. After crystallization from water, 0.10 g. of the title compound is obtained which melts at 203°-205° C.

Workup

  1. concentrationthe solution is concentrated to a small volume
  2. customthe solid which precipitates
  3. customis collected on the filter
  4. customAfter crystallization from water, 0.10 g

Sources & evidence

ORD record
ord-80cf3cf2fa9e4eda8c9604b6b74fd614
Source dataset
uspto-grants-1976_10
Patent number
US03987053

Reaction notes

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