Hydrochloric Acid → HCID 178478867, compound

HRID 1288112Notes

Reaction equation

HRID 1288112 reaction equation
[OH:1][C:2]1[C:11]2[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=2[N:5]=[C:4]2[CH2:12][CH2:13][CH2:14][N:15](C(OC3C=CC=CC=3)=O)[CH2:16][C:3]=12.[ClH:26].C1(N)C(F)=C(F)C(F)=C(N)C=1F.Cl.Cl>>[ClH:26].[ClH:26].[OH:1][C:2]1[C:11]2[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=2[N:5]=[C:4]2[CH2:12][CH2:13][CH2:14][NH:15][CH2:16][C:3]=12

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 149026Tetrafluoro-m-phenylenediamine dihydrochlorideHCID 178524303HCID 178524303, compound

Product 1

HCID 178478867HCID 178478867, compound

Procedure

11-Hydroxy-2,3,4,5-tetrahydro-1H-azepino[4,3-b]quinoline dihydrochloride was prepared by hydrolysis of 11-hydroxy-2-phenoxycarbonyl-2,3,4,5-tetrahydro-1H-azepino[4,3-b]quinoline with concentrated hydrochloric acid. Yield of the dihydrochloride: 65% of theory; m.p. 289° C. (decomp.).

Sources & evidence

ORD record
ord-fa515954e0724f98bf55d4b3b6b3618f
Source dataset
uspto-grants-1976_10
Patent number
US03987047

Reaction notes

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