Methyl iodide → HCID 54430515, compound

HRID 1288508Notes

Reaction equation

HRID 1288508 reaction equation
[CH2:1]([P:7]([O:12][CH2:13][CH3:14])(=[O:11])[O:8][CH2:9][CH3:10])[CH:2]=[CH:3][CH2:4][CH:5]=[CH2:6].CI.[CH2:17](P(OCC)(=O)OCC)C=CC.C(Br)C1C=CC=CC=1>>[CH3:17][CH:1]([P:7]([O:8][CH2:9][CH3:10])(=[O:11])[O:12][CH2:13][CH3:14])[CH:2]=[CH:3][CH2:4][CH:5]=[CH2:6]

Participants

5

Reactant 4

HCID 6328Methyl iodideHCID 7498Benzyl BromideHCID 23280288HCID 23280288, compoundHCID 54280522HCID 54280522, compound

Product 1

HCID 54430515HCID 54430515, compoundYield 93%

Procedure

The same procedure as in Example A-1 was repeated except that 2.18 g of diethyl 2,5-hexadienephosphonate and 1.42g of methyl iodide were used instead of 1.92 g of the diethyl 2-butenephosphonate and 1.7 g of the benzyl bromide respectively. Vacuum distillation of the reaction mixture afforded 2.15 g of diethyl 1-methyl-2,5-hexadienephosphonate having a boiling point of 102° C. (3 mmHg) in yield of 93%.

Workup

  1. distillationVacuum distillation of the reaction mixture

Sources & evidence

ORD record
ord-0e3dbd4d0f5443bc9d760e48cb219722
Source dataset
uspto-grants-1976_10
Patent number
US03988380

Reaction notes

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