反应详情

A mixture of 11.0 g. of 2-chloromethyl-6-methylnaphthalene, 7.0 g. of sodium carbonate and 10.0 g. of 2-pyridylpiperazine in 75 ml. of dimethylformamide is stirred for six hours. The reaction mixture is cooled, filtered and the filtrate is concentrated. The precipitate is then washed with water and crystallized from ethanol to yield 1-(6-methyl-β-naphthylmethyl)-4-(2-pyridyl)piperazine.

1. additionA mixture of 11.0 g
2. temperatureThe reaction mixture is cooled
3. filtrationfiltered
4. concentrationthe filtrate is concentrated
5. washThe precipitate is then washed with water
6. customcrystallized from ethanol