反应详情

A solution of titanium tetrachloride (10.4 g) in n-hexane (30 ml) was added dropwise with stirring to a solution of cyclopropyl methyl ketone (8.4 g) and diethylamine (43.9 g) in n-hexane (100 ml) whilst maintaining the temperature below 25° C. The mixture was stirred for 5 hours, filtered and the filtrate was evaporated to dryness to give 1-cyclopropyl-1-diethylaminoethene (5.3 g) as a pale yellow oil, NMR (CDCl3) d=0.5-0.8(m, 4H), 1.1(t, 6H), 1.4(m, 1H), 3.2(q, 4H), 3.45(s, 1H), 3.5(s, 1 H).

1. temperaturewhilst maintaining the temperature below 25° C
2. filtrationfiltered
3. customthe filtrate was evaporated to dryness