反应详情

温度

80 °C

Suspended in 50 ml of 1N sodium hydroxide were 16.5 g of ethyl [2-[(4-chlorophenyl)sulfonylaminomethyl]indan-5-yl]-acetate, and the suspension was heated at 80° C. for 1 hour. After cooling, hydrochloric acid was added to the suspension to acidify it. A crystal deposited was collected by filtration. The crystal was recrystallized from 80% ethanol to obtain 14.0 g of the title compound as a colorless needle crystal. Yield: 91%.

1. temperatureAfter cooling
2. filtrationA crystal deposited was collected by filtration
3. customThe crystal was recrystallized from 80% ethanol