Sodium Iodide → HCID 178506581, compound

HRID 1289611Notes

Reaction equation

HRID 1289611 reaction equation
S([O-])(=O)(=O)C.[I-:6].[Na+].[CH3:8][C:9]([CH2:11][CH3:12])=O>>[I:6][CH2:8][C@H:9]1[CH2:12][CH2:11][C@H:9]([CH2:8][I:6])[CH2:12][CH2:11]1

Participants

4

Reactant 3

HCID 5238Sodium IodideHCID 6569Methyl Ethyl KetoneHCID 85257Methanesulfonate

Product 1

HCID 178506581HCID 178506581, compound

Procedure

Add 30 gms. of the mesylate prepared in step (a) to 300 ml. methylethyl ketone (MEK), then add 90 gm. sodium iodide and reflux for about 30 minutes. Remove the solvent and extract with methylene chloride to yield trans 1,4-bis iodomethyl cyclohexane.

Workup

  1. additionAdd 30 gms
  2. customRemove the solvent
  3. extractionextract with methylene chloride

Sources & evidence

ORD record
ord-b9c0f1cfe03e45848f9b3839cb6c9472
Source dataset
uspto-grants-1998_05
Patent number
US05750532

Reaction notes

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