Hydrazine → HCID 178509289, compound

HRID 1289782Notes

Reaction equation

HRID 1289782 reaction equation
[CH:1]1[CH:6]=[CH:5][C:4]([O:7][C:8](OC2C=CC=CC=2)=[N:9][C:10]#[N:11])=[CH:3][CH:2]=1.[NH2:19][NH2:20]>CO>[NH2:11][C:10]1[N:9]=[C:8]([O:7][C:4]2[CH:5]=[CH:6][CH:1]=[CH:2][CH:3]=2)[NH:20][N:19]=1

Participants

4

Reactant 2

HCID 9321HydrazineHCID 688090Diphenyl N-Cyanocarbonimidate

Product 1

HCID 178509289HCID 178509289, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Diphenylcyanocarbonimidate (9.53 g) and methanol (150 ml) were cooled to 0° C. and hydrazine (1.5 ml) was gradually added dropwise thereto. The mixture was stirred at 0° C.-room temperature for 2 hours. Methanol was distilled away under reduced pressure and the residue was subjected to silica gel column chromatography (chloroform-methanol) to quantitatively give white crystals.

Workup

  1. distillationMethanol was distilled away under reduced pressure

Sources & evidence

ORD record
ord-f73325d073c649d6b95c50bc555f567d
Source dataset
uspto-grants-1998_05
Patent number
US05750545

Reaction notes

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