1,2-Dichloroethane → Phenylpropynoic acid methyl ester

HRID 1289789Notes

Reaction equation

HRID 1289789 reaction equation
[C:1]1([C:7]#[C:8][C:9]([OH:11])=[O:10])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.Cl[CH2:13]CCl.S(=O)(=O)(O)O>CO>[C:1]1([C:7]#[C:8][C:9]([O:11][CH3:13])=[O:10])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

5

Reactant 3

HCID 111,2-DichloroethaneHCID 1118Sulfuric AcidHCID 69475Phenylpropiolic Acid

Product 1

HCID 138378Phenylpropynoic acid methyl ester

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The synthesis method of Example 7-(1) was applied. Phenylpropiolic acid (5.16 g), : 1,2-dichloroethane (40 ml), methanol (5 ml) and concentrated sulfuric acid (0.2 ml) were used as reagents to quantitatively give a colorless transparent liquid.

Workup

  1. customto quantitatively give a colorless transparent liquid

Sources & evidence

ORD record
ord-f0547759d04a4c568d460899e2bc80dc
Source dataset
uspto-grants-1998_05
Patent number
US05750545

Reaction notes

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