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HRID1289958

反应详情

EQUATION

反应方程式

HRID 1289958 的结构方程式

REACTANTS

反应物

2
结构：O=C(O)C(F)(F)F
HCID6422

未命名化合物

结构：C[C@@H](O[C@H]1CC[C@@H](N(C)CC(=O)OC(C)(C)C)[C@@H]1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1
HCID22885705

未命名化合物

PRODUCTS

生成物

1
结构：C[C@@H](O[C@H]1CC[C@@H](N(C)CC(=O)O)[C@@H]1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1
HCID22885700

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：COc1ccccc1
催化剂HCID7519

Anisole

C7H8O

PROCEDURE

实验过程

To 280 mg of t-butyl ester from Step A was added 2 drops of anisole and 4 mL of TFA. After 75 min the volatiles were removed in vacuo followed by evaporation of two portions of methylene chloride. The residue was used directly in the Step C.

WORKUP

后处理

  1. customAfter 75 min the volatiles were removed in vacuo
  2. customfollowed by evaporation of two portions of methylene chloride