反应详情

To a solution of 5-bromosalicylaldehyde (5.0 gm, 0.025 mol) in DMF (40 mL) were added powdered potassium carbonate (5.15 gm, 0.037 mol) and 2-iodopropane (3.5 mL, 0.035 mol) dropwise with stirring. The mixture was stirred overnight at room temperature, partitioned between diethyl ether and water. The aqueous was extracted with ether, and the combined organic layers were washed with water, saturated brine solution, dried (Na2 SO4), and evaporated to afford 6.0 gm of pure title compound.

1. stirringThe mixture was stirred overnight at room temperature
2. custompartitioned between diethyl ether and water
3. extractionThe aqueous was extracted with ether
4. washthe combined organic layers were washed with water, saturated brine solution
5. customdried (Na2 SO4)
6. customevaporated