Water → HCID 86752476, compound

HRID 1290391Notes

Reaction equation

HRID 1290391 reaction equation
[OH-].[OH:2][P:3]([O:14][CH2:15][CH:16]1[CH2:20][CH:19]([S:21][C:22]2[CH:28]([CH3:29])[CH:27]3[N:24]([C:25](=[O:33])[CH:26]3[CH:30]([OH:32])[CH3:31])[C:23]=2[C:34]([O:36]CC2C=CC([N+]([O-])=O)=CC=2)=[O:35])[CH2:18][O:17]1)([O:5][CH2:6][CH2:7][N+:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)=[O:4].C(=O)(O)[O-].[Na+].O>[Pd].O1CCOCC1>[OH-:2].[C:34]([C:23]1[N:24]2[CH:27]([CH:28]([CH3:29])[C:22]=1[S:21][CH:19]1[CH2:18][O:17][CH:16]([CH2:15][O:14][P:3]([OH:4])([O:5][CH2:6][CH2:7][N+:8]3[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=3)=[O:2])[CH2:20]1)[CH:26]([CH:30]([OH:32])[CH3:31])[C:25]2=[O:33])([OH:36])=[O:35]

Participants

6

Reactant 3

HCID 962WaterHCID 516892Sodium BicarbonateHCID 86752478HCID 86752478, compound

Product 1

HCID 86752476HCID 86752476, compoundYield 130.7%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 312751,4-DioxaneSolvent

Procedure

The title compound is prepared by the procedure of Example 18 using 0.150 g of product from Example 95, 0.025 g of sodium bicarbonate, 3 ml of water, 9 ml of dioxane and 0.030 g of 10% palladium/carbon to give 0.0786 g of the desired product.

Sources & evidence

ORD record
ord-1eae863e9f304242bc6f04075245a755
Source dataset
uspto-grants-1998_05
Patent number
US05750735

Reaction notes

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