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HRID1292364

反应详情

EQUATION

反应方程式

HRID 1292364 的结构方程式

REACTANTS

反应物

3
结构：Cc1ccc(S(=O)(=O)O)cc1.O
HCID521998

4-Methylbenzenesulfonic acid hydrate

C7H10O4S

结构：NC(=O)[C@H](CCC(=O)O)NC(=O)OCc1ccccc1
HCID6992292

未命名化合物

结构：CC#N.CC(=O)O.[H][H]
HCID178464491

未命名化合物

PRODUCTS

生成物

1
结构：CCOC(=O)CC[C@H](NC(=O)OCc1ccccc1)C(N)=O
HCID18637511

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCO
溶剂HCID702

Ethanol

C2H6O

PROCEDURE

实验过程

A stirred suspension of carbobenzyloxyisoglutamine (28 g, 100 mmol) and p-toluenesulfonic acid monohydrate (1.9 g, 10 mmol) in 560 mL of absolute ethanol was gently refluxed for 12-14 hours or until TLC (1:5:94 HOAc/H2 /CH3CN) indicated that the reaction was complete.