Sodium sulfate decahydrate → HCID 17861367, compound

HRID 1294156Notes

Reaction equation

HRID 1294156 reaction equation
[CH3:1][O:2][CH2:3][O:4][C:5]1[CH:14]=[CH:13][C:12]([CH2:15][CH2:16][CH3:17])=[CH:11][C:6]=1[C:7](OC)=[O:8].[H-].[Al+3].[Li+].[H-].[H-].[H-].O.O.O.O.O.O.O.O.O.O.[O-]S([O-])(=O)=O.[Na+].[Na+]>O1CCCC1>[CH3:1][O:2][CH2:3][O:4][C:5]1[CH:14]=[CH:13][C:12]([CH2:15][CH2:16][CH3:17])=[CH:11][C:6]=1[CH2:7][OH:8]

Participants

5

Reactant 3

HCID 62649Sodium sulfate decahydrateHCID 17861389HCID 17861389, compoundHCID 21226445Aluminium lithium hydride

Product 1

HCID 17861367HCID 17861367, compoundYield 93.1%

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

To a mixture of methyl 2-methoxymethoxy-5-propylbenzoate (6.06 g) and tetrahydrofuran (200 mL) was added lithium aluminum hydride (0.96 g) under ice-cooling, and the mixture was stirred at room temperature for 1 hr. To the mixture was added sodium sulfate 10 hydrate (8.18 g) and the mixture was further stirred at room temperature for 30 min. The insoluble materials were removed by filtration, and the filtrate was concentrated to give (2-methoxymethoxy-5-propylphenyl)methanol as an oil (4.98 g, 93%).

Workup

  1. temperaturecooling
  2. stirringthe mixture was further stirred at room temperature for 30 min
  3. customThe insoluble materials were removed by filtration
  4. concentrationthe filtrate was concentrated

Sources & evidence

ORD record
ord-d525c5612ef04bcaad940d42e7c1d1a2
Source dataset
uspto-grants-2007_07
Patent number
US07238716B2

Reaction notes

Loading…