HRID1294362

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID313

Hydrochloric Acid

ClH

结构：CCOC(=O)[C@@H]1C[C@H]1c1ccc(B2OC(C)(C)C(C)(C)O2)cc1

HCID66578250

未命名化合物

PRODUCTS

生成物

结构：CC1(C)OB(c2ccc([C@@H]3C[C@H]3C(=O)O)cc2)OC1(C)C

HCID67494736

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID14798

Sodium Hydroxide

HNaO

CONDITIONS

反应条件

温度: 100 °C

PROCEDURE

实验过程

A mixture of ester from step 2 and NaOH (20%, 30 mL) was heated to 100° C. for 1.5 h, cooled to rt, acidified with HCl 10% and extracted with EtOAc. The organic extract was dried over Na2SO4 and the solvent evaporated to afford the title compound.

WORKUP

后处理

temperaturecooled to rt
extractionextracted with EtOAc
extractionThe organic extract
dry with materialwas dried over Na2SO4
customthe solvent evaporated