HCID 22929889, compound → HCID 22929650, compound

HRID 1295929Notes

Reaction equation

HRID 1295929 reaction equation
[N:1]([CH2:4][C:5]1[C:17]([C:18]#[N:19])=[CH:16][C:8]([C:9]([O:11]C(C)(C)C)=[O:10])=[C:7]([O:20][CH2:21][CH3:22])[CH:6]=1)=[N+:2]=[N-:3]>ClCCl.FC(F)(F)C(O)=O>[N:1]([CH2:4][C:5]1[C:17]([C:18]#[N:19])=[CH:16][C:8]([C:9]([OH:11])=[O:10])=[C:7]([O:20][CH2:21][CH3:22])[CH:6]=1)=[N+:2]=[N-:3]

Participants

4

Reactant 1

HCID 22929889HCID 22929889, compound

Product 1

HCID 22929650HCID 22929650, compound

Reagents, catalysts & solvents 2

HCID 6344DichloromethaneSolventHCID 6422Trifluoroacetic acidSolvent

Procedure

After dissolving tert-butyl 4-(azidomethyl)-5-cyano-2-ethoxybenzoate (1.923 g) in dichloromethane (12 ml), trifluoroacetic acid (3 ml) was added while cooling on ice. The mixture was stirred at room temperature for 20 minutes and concentrated. The title compound was obtained as light red crystals.

Workup

  1. additionwas added
  2. temperaturewhile cooling on ice
  3. concentrationconcentrated

Sources & evidence

ORD record
ord-bdea8125bf704f8a93b3d585594e51a5
Source dataset
uspto-grants-2007_07
Patent number
US07244730B2

Reaction notes

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