反应详情

After dissolving the N1-methyl-4-(azidomethyl)-5-bromo-2-ethoxybenzamide (5.32 g) in tetrahydrofuran (50 ml) and water (3 ml), triphenylphosphine (5.4 g) was added and the mixture was stirred at room temperature for 4 days. The reaction mixture was concentrated and the residue was purified by silica gel column chromatography (solvent: n-hexane-ethyl acetate) to yield the title compound (5.11 g) as a light yellow solid.

1. additionwas added
2. concentrationThe reaction mixture was concentrated
3. customthe residue was purified by silica gel column chromatography (solvent: n-hexane-ethyl acetate)