Potassium Carbonate → HCID 18186916, compound

HRID 1296643Notes

Reaction equation

HRID 1296643 reaction equation
[CH2:1]([N:8]1[CH2:13][CH2:12][NH:11][CH:10]([CH2:14][CH3:15])[CH2:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[Cl:16][C:17]1[CH:22]=[N:21][CH:20]=[C:19](Cl)[N:18]=1.C([O-])([O-])=O.[K+].[K+]>>[CH2:1]([N:8]1[CH2:13][CH2:12][N:11]([C:19]2[CH:20]=[N:21][CH:22]=[C:17]([Cl:16])[N:18]=2)[CH:10]([CH2:14][CH3:15])[CH2:9]1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 3

HCID 11430Potassium CarbonateHCID 785042,6-DichloropyrazineHCID 220365411-Benzyl-3-ethylpiperazine

Product 1

HCID 18186916HCID 18186916, compound

Procedure

The title compound was prepared according to the procedure of example 39, step 2, starting from the product obtained in step 1 above (4.60 g, 22.5 mmol), 2,6-dichloropyrazine (3.90 g, 26.2 mmol) and K2CO3 (6.22 g, 45.0 mmol). Yield: 6.15 g (86%). MS m/z 316/318 (M)+ (35Cl/37Cl-isotope pattern). HRMS m/z calcd for C17H21ClN4 (M)+ 316.1455, found 316.1455.

Sources & evidence

ORD record
ord-123083806e1244809b7871dc5c6e47ea
Source dataset
uspto-grants-2007_07
Patent number
US07247633B2

Reaction notes

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