Acetic Anhydride → HCID 58913640, compound

HRID 1296868Notes

Reaction equation

HRID 1296868 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][C:9]([C:11]2[CH:16]=[C:15]([Cl:17])[C:14]([OH:18])=[CH:13][C:12]=2[OH:19])=[O:10])=[CH:4][CH:3]=1.[C:20](OC(=O)C)(=O)[CH3:21].C(=O)([O-])[O-].[K+].[K+]>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[C:9](=[O:10])[C:11]3[C:12](=[CH:13][C:14]([OH:18])=[C:15]([Cl:17])[CH:16]=3)[O:19][C:20]=2[CH3:21])=[CH:6][CH:7]=1

Participants

4

Reactant 3

HCID 7918Acetic AnhydrideHCID 11430Potassium CarbonateHCID 58913651HCID 58913651, compound

Product 1

HCID 58913640HCID 58913640, compound

Procedure

This compounds was synthesised in the same manner as described above. 2-(4-Bromo-phenyl)-1-(5-chloro-2,4-dihydroxy-phenyl)-ethanone (1.5 g, 4.4 mmol), Acetic anhydride (2.0 ml), Potassium carbonate (2.1 g 15.2 mmol). 3-(4-Bromo-phenyl)-6-chloro-7-hydroxy-2-methyl-chromen-4-one was obtained an off white solid (1.2 g, 74.5%).

Workup

  1. customThis compounds was synthesised in the same manner

Sources & evidence

ORD record
ord-af45297177b242908863cf2422ffb449
Source dataset
uspto-grants-2007_07
Patent number
US07247734B2

Reaction notes

Loading…