Hydrazine hydrate (1:1) → HCID 178435604, compound

HRID 1296898Notes

Reaction equation

HRID 1296898 reaction equation
[CH2:1]([C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][C:12]=1[OH:13])[O:9][CH:8]=[C:7]([C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)[C:6]2=O)[CH3:2].O.[NH2:22][NH2:23]>C(O)C>[CH2:1]([C:3]1[CH:4]=[C:5]([C:6]2[C:7]([C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)=[CH:8][NH:23][N:22]=2)[C:10]([OH:9])=[CH:11][C:12]=1[OH:13])[CH3:2]

Participants

4

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 53996516-Ethyl-7-hydroxy-3-phenyl-chromen-4-one

Product 1

HCID 178435604HCID 178435604, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

This compounds was synthesised in the same manner as described above. 6-Ethyl-7-hydroxy-3-phenyl-chromen-4-one (0.29 g, 1.1 mmol), hydrazine hydrate (4 ml), ethanol (20 ml). The crude product was columned to give 4-Ethyl-6-(4-phenyl-1H-pyrazol-3-yl)-benzene-1,3-diol as a off white solid (0.23 g, 74.73%); Rf 0.7 Cf SM 0.9 ethyl acetate/hexane (70/30).

Workup

  1. customThis compounds was synthesised in the same manner

Sources & evidence

ORD record
ord-1d4679dcdfe0406cad8c4454bcf1f803
Source dataset
uspto-grants-2007_07
Patent number
US07247734B2

Reaction notes

Loading…