Nitrogen → 5-Methyl-2-(propan-2-yl)hexanal

HRID 132733Notes

Reaction equation

HRID 132733 reaction equation
[CH:1]([C:4](=[CH:7][CH2:8][CH:9]([CH3:11])[CH3:10])[CH:5]=[O:6])([CH3:3])[CH3:2].C([O-])(O)=O.[Na+].N#N>[Pd].C(O)C>[CH:1]([CH:4]([CH2:7][CH2:8][CH:9]([CH3:11])[CH3:10])[CH:5]=[O:6])([CH3:3])[CH3:2]

Participants

6

Reactant 3

HCID 947NitrogenHCID 370662-(1-Methylethyl)-5-methylhex-2-enalHCID 516892Sodium Bicarbonate

Product 1

HCID 30177025-Methyl-2-(propan-2-yl)hexanal

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

To 10 g 2-isopropyl-5-methyl-2-hexenal synthesized above were added 70 ml ethanol, 1 ml saturated NaHCO3 solution and 0.25 g 10% Pd on carbon. N2 was introduced, follwed by H2, and the apparatus was connected with a graduated titration tube filled with H2. The reaction was allowed to continue with stirring at room temperature and atmosphere pressure until the absorption of H2 reached calculation value. The reaction mixture was filtered and the filtrate was used in the next step.

Workup

  1. customthe apparatus was connected with a graduated titration tube
  2. additionfilled with H2
  3. customatmosphere pressure until the absorption of H2 reached calculation value
  4. filtrationThe reaction mixture was filtered

Sources & evidence

ORD record
ord-83c0131379074ee7bbeb4057ca6c9922
Source dataset
uspto-grants-2008_06
Patent number
US07388061B2

Reaction notes

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