Dichloromethane → 2-(1H-benzimidazol-1-yl)-N-(3-chloro-4-fluorophenyl)acetamide

HRID 134328Notes

Reaction equation

HRID 134328 reaction equation
[C:8](=[O:9])([OH:10])[CH2:11][n:12]1[cH:13][nH+:14][c:15]2[c:16]1[cH:17][cH:18][cH:19][cH:20]2.[CH2:39]1[O:40][CH2:41][CH2:42][CH2:43]1.[Cl:21][c:22]1[cH:23][c:24]([NH2:25])[cH:26][cH:27][c:28]1[F:29].[Cl:30][C:31]([C:32]([Cl:33])=[O:34])=[O:35].[Cl:36][CH2:37][Cl:38].[F:1][C:2]([F:3])([F:4])[C:5]([O-:6])=[O:7]>>[C:8](=[O:10])([CH2:11][n:12]1[cH:13][n:14][c:15]2[c:16]1[cH:17][cH:18][cH:19][cH:20]2)[NH:25][c:24]1[cH:23][c:22]([Cl:21])[c:28]([F:29])[cH:27][cH:26]1

Participants

7

Reactant 6

HCID 6344DichloromethaneHCID 8028TetrahydrofuranHCID 97083-Chloro-4-fluoroanilineHCID 65578Oxalyl chlorideHCID 84468TrifluoroacetateHCID 178525836HCID 178525836, compound

Product 1

HCID 64576052-(1H-benzimidazol-1-yl)-N-(3-chloro-4-fluorophenyl)acetamide

Sources & evidence

ORD record
ord-a3256596430548c68fd16baf15839dac
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

Loading…